Acne treatment is performed in a variety of ways. These are cosmetics, salon techniques, and various medicines. In particularly severe cases, acne is prescribed for antibiotics to eliminate acne. One of them is Doxycycline – the acne is treated by the substance doxycycline hydrochloride, which is present in the drug composition. This antimicrobial agent of a wide spectrum of activity belongs to the group of antibiotics-tetracyclines.
It is available in the capsules of 50, 100 and 200 mg or powder, from which the solution for intravenous infusions is prepared by dilution. The bacterial pathogens act bacteriostatically. The drug suppresses the reproduction and growth of microbes, preventing the synthesis of the necessary for the formation of cellular structures of the protein.
Doxycycline is susceptible to virtually all the most significant pathogens of infections: E. coli, staphylococcus and streptococci, salmonella, mycoplasma, chlamydia, klebsiella, rickettsia and many others. They are the most common cause of diseases of the internal organs, accompanied by the appearance on the skin of various rashes and acne.
What is Acne?
Acne is a condition of the skin that occurs due to changes in the hormonal level, particularly during puberty in adolescence. Hormones, known as androgens, affect the glands that release sebum into small holes on the skin – pores. In the development of acne, four main mechanisms can be distinguished:
- increased production of sebaceous secretion by sebaceous glands;
- hyperkeratosis – excessive thickening of the upper (corneal) layer of the skin;
- the activity of the microflora of the skin, i.e. those bacteria that normally dwell on the human skin;
Clinical manifestations of acne:
It is accepted to distinguish between several clinical varieties of this disease. Vulnerary or juvenile, papular and pustular acne are referred to lighter and relatively favorable forms. They are easier to treat and usually leave no coarse scar changes on the skin after themselves. On the contrary, indurational, efflux, phlegmonous and conglomerate acne due to the resistance to therapy, frequent relapses and the appearance of these forms of rough cosmetic defects present a complicated medical and socio-psychological problem for the physician and the patient.
A professional dermatologist, inspecting the face and other affected areas of the body, is able to correctly determine the type of acne. Comprehensive examination and the appointment of competent treatment (for example, laser procedures) will help get rid of anxiety symptoms. Due to increased production, the secretion of sebaceous gland increases in size, which leads to the appearance of ugly enlarged pores on the face. At the mouth of its duct, thick layer of scales of the skin thickens, which tends faster than usual. Soon the flakes clog the duct and clog it.
The sebaceous gland stretches the cavity of the sebaceous gland, in which it gradually accumulates more and more. Propionobacterium bacteria begins to reproduce in the closed gland of the sebaceous glands. This bacterium is a normal representative of the microflora of the sebaceous glands, but when it breeds too much, there is an inflammation.
Clogged sebaceous gland, filled with sebum, is called comedone. If comedon does not have an appearance on the surface of the skin, the skin remains white and white acne occurs. If comedon goes out on the surface, the bark’s fat is partially oxidized, melanin is added to it, resulting in the comedone’s head becoming black – black acne appears.
Acne rash can occur for a variety of reasons. That is why, when it occurs, it is worth turning to the dermatologist – the doctor will find out what exactly led to the appearance of acne and appoint appropriate treatment. If it turns out that an acne is caused by hormonal disorders, you will also need an endocrinologist’s consultation. The cosmetologist, in turn, will help get rid of external manifestations of the disease.
Causes of Acne:
- Changes in hormonal balance. This is the most common cause of acne in adolescents during puberty. The main provocative factor in adolescence is the increase in the blood of male sex hormones androgens, under the influence of which the sebaceous glands increase in size and begin to secrete more sebum. In girls and women, changes in hormonal balance can cause acne during menstrual cycles, and may also be associated with the use of contraceptives.
- Reduced immunity and dysfunction of the gastrointestinal tract. The ability to parasitize and actively propagate bacteria on the skin provides, including reduced immunity. The healthy intestinal microflora is 70% immunity, which is an obstacle in the path of infection, causing the formation of new acne. In addition, healthy immunity provides effective healing of already existing acne.
- Acne may appear in people who are constantly experiencing severe stressful situations, and may also be the result of chronic overwork. Extreme stresses on experiences with friends and parents can really affect the health of young skin.
- The use of comedogenic cosmetics. Some cosmetic products – creams, lotions and blush – contain lanolin, sulfur, vaseline, paraffin, mineral and vegetable oils, as well as red pigments. These ingredients are able to provoke the appearance of acne. As a rule, many use special cosmetics for their masking of inflammatory elements (powders, tonal creams), which burdens the course of the disease. A so-called closed circle forms, which complicates the treatment of acne.
- The wrong skin care. In many cases, the cause of the spread of acne is the wrong skin care. As a result of self-removing dying skin cells and self-medication, for example, widespread extrusion of black dots and pustules, the epidermis is damaged, and the infection gets ways for further spread.
- Environmental factors. Changes in climatic conditions play a significant role in the intensity of the appearance of acne and area of defeat. Many believe that winter is the worst time for acne due to severe weather conditions that lead to dryness and scaling of the skin. However, in winter use of additional moisturizers can only increase the rash.
Doxycycline Dosage for Acne
Doctors prescribe doxycycline in cases of moderate and severe acne. The degree of these staages are determined by the presence in the human organism of gram-positive, gram-negative, spore-forming and non-spore-forming strains of pathogenic microorganisms. The standard dosage is: 100 mg of the drug in the morning and evening during the week. As a rule, adults and children who are 14 years of age, in the first days of treatment, are prescribed the drug once a day, in the dosage of 200 mg. In the following days – 100 mg per day.
For children 9-14 years of age, the dosage is determined depending on the body weight: 4 mg per kilogram of weight. On the first day – twice a day, then – twice a day, but already 2-3 mg per kilogram of weight.
How Long to Take Doxycycline for Acne?
The use of Doxycycline for acne is often justified, but before taking the drug and starting treatment, we recommend that you must go through the examination and get expert advice. Be careful, because if you treat the problem incorrectly, then the body may not get a positive effect. The drug should be taken either with milk or with plenty of water. The treatment is recommended to be supplemented by the use of drugs that prevent the onset of dysbiosis and stomach pain. Also, those who take doxycycline for acne should increase the intake of sour-milk products: rye-breads, yoghurts, kefir. The duration of the course of antibiotic therapy is determined by the physician individually.
Doxycycline for Acne Side Effects
Because of the toxicity of the drug, there can also be negative reactions of the organism to it. Most commonly, dyspepsia, stool disorders (both diarrhea and constipation), painful sensations in epigastrium and intestines. Manifestations and disorders in the work of the nervous system in the form of headaches, dizziness are also possible.
The administration of Doxycycline with acne and other skin rashes is also fraught with allergies such as itching and rash, and in rare cases, photosensitization and Quincke’s edema. Often, the process of hematopoiesis is violated, which leads to hemolytic anemia, a decrease in the number of platelets, eosinophils, and other shaped elements. In children, antibiotic therapy with tetracyclines is characterized by darkening of the tooth enamel.